Delayed Huntington's disease diagnosis in two alcoholic patients with a family history of "Parkinson's disease".

To the Editor: Huntington’s disease is an autosomal dominant neurodegenerative disease characterized by a triad of symptoms and signs including movement disorder, cognitive impairment, and behavioral syndromes. As the earliest pathological changes in Huntington’s disease are in the associative portion of the striatum, the domains first affected by the disease may be cognitive and psychiatric rather than motor.